section 8 handout_answers

section 8 handout_answers - Bio1A Spring 2011 Discussion...

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Bio1A Spring 2011 Discussion Section Handout #8 Week of March 28, 2011 The Genetic Code 1) a. What does it mean that the genetic code is (almost) universal? What does this tell us about the evolution of the code? Why is this universality useful for biologists? The genetic code is conserved in almost all species. (UUU = phenylalanine in all organisms.) There are only a handful of exceptions, for example stop codons can encode special amino acids like selenocysteine. This is useful for biologists because we can take sequences from one organism, put them into another organism, and they will still express the same protein sequence. b. What does it mean that the genetic code is partially redundant? How does this redundancy protect against mutations in protein sequence? There are multiple codons for each amino acid. This buffers against mutations by providing some interchangeable nucleotides, where changing them will not affect the final protein sequence. The most common mutations are transitions; these usually result either in no amino acid change or a change to a similar amino acid. Translation 1) Translate the following partial mRNA sequence (first find the start codon!): 5’ ACUCG AUG AAG UUU AGU GUG GAC ACA CAC GUC UAA GCCG 3’
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START(Met) Lys Phe Ser Val Asp Thr His Val STOP 2) What is the 5’ to 3’ sequence of the template DNA strand at this locus?
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section 8 handout_answers - Bio1A Spring 2011 Discussion...

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