Hypercalcemia - Page 1 Thieny Nguyen Professor Khalil MEDA...

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Page 1 Thieny Nguyen Professor Khalil MEDA 115 Feb 23 2009 Project 1 Hypercalcemia Hypercalcemia is an increased level of calcium in the bloodstream (total plasma Ca concentration > 10.4 mg/dL (> 2.60mmol/L) or ionized plasma Ca > 5.2 mg/dL (> 1.30mmol/L)). The common cause is malignancy, vitamin D toxicity or primary hyperparathyroidism (Merck 1254). In Essentials of Diseases and Conditions, there is not any specific description of hypercalcemia. Hypercalcemia was discussed quite briefly in hyperparathyroidism’s description. (Frazier 173). Etiology In the case of hypercalcemia, bone metastases cause an imbalance between bone formation and bone resorption, resulting in the release of excess calcium into the blood. The most common cause is iatrogenic, from excess Ca or vitamin D, or phosphate deprivation, which can result from prolonged feeding with incorrectly prepared formula or from dairy milk containing excess vitamin D. Other causes include maternal hypoparathyroidism, subcutaneous
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Hypercalcemia - Page 1 Thieny Nguyen Professor Khalil MEDA...

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