g55.docx - Spinal cord compression Patients with haematological disease may present with spinal cord compression This may be due to tumour deposits such

g55.docx - Spinal cord compression Patients with...

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Spinal cord compression Patients with haematological disease may present with spinal cord compression. This may be due to tumour deposits, such as lymphoma or plasmacytoma, or a consequence of spinal instability from lytic bone disease in multiple myeloma. Most patients with cord compression complain of pain, which is constant and can be easily confused with degenerative disease. Commonly, signs consistent with root compression, with pain in the affected dermatome, precede the overt signs of cord compression. The neurological signs accompanying cord compression vary according to both the rapidity of the development of compression and the area of the cord affected (Box 14.3). Acute lesions often result in hypotonia and weakness, whereas chronic lesions are more often associated with the classic upper motor neurone signs of (a) (b) Figure 14.4 Sickle cell disease. Anteroposterior chest radiographs: (a) at presentation showing generalised air space change/consolidation in the lower zone of the right lung; (b) showing progressive air space changes in the right lower zone a day following presentation. Source: S Yale, N Nagib, and T Guthrie. Acute chest syndrome in sickle cell disease: crucial considerations in adolescents and adults. Postgraduate Medicine, Vol 107:No. 1:Jan 2000. Reproduced with permission of Taylor & Francis. Figure 14.5 Sickled red cells (crescent shaped) in homozygous sickle
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  • Fall '16
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  • Spinal Cord Compression

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