Lect2 - Mendelian_Genetics

Lect2 - Mendelian_Genetics - Divisions of Genetics...

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Divisions of Genetics Transmission – how traits are passed on Molecular – chemical nature of gene Population – groups of individuals
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Mendelian Genetics
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Divisions of Genetics Transmission Molecular Population
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Lecture outline Mendel’s principles of Genetics Monohybrid and Dihybrid crosses Chi square analysis Pedigrees
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Gregor Mendel Augustinian monk Teacher and experimentalist Discovered discrete units of inheritance Determined principles of inheritance Basis for transmission genetics
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Mendel’s experimental method Model organism: Pisum sativum Easy to grow, hybridize artificially Grows to maturity in single season Followed contrasting pairs of traits Height, seed shape and color, pod shape and color, pod and flower arrangement Accurate quantitative records
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Traits Studied by Mendel
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Monohybrid cross Start with pure breeders with contrasting traits Mate them (P 1 )and analyze offspring (F 1 ) Self-fertilization of F 1 Ratios were consistent, even in reciprocal crosses Mendel then proposed unit factors to explain
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Description of Mendel’s results Binary results, contribution of two individuals Disappearance of trait in F1 Reappearance in F2
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Postulates from Monohybrid cross For a specific trait, unit factors occur in pairs When unit factors control contrasting traits, one unit factor is dominant to the other.
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