Lect17-Genomics_Proteomics

Lect17-Genomics_Proteomics - DNASequencing gene...

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DNA Sequencing Determine actual nucleotide sequence of  gene Developed by James Sanger Based on Dideoxynucleotide termination Separated by polyacrylamide gel  electrophoresis (1 nucleotide resolution)
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Genomics and Proteomics
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Outline Genomics overview Structural genomics Functional genomics The Human Genome Project Comparitive genomics Proteomics
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Outline Genomics overview Structural genomics Functional genomics The Human Genome Project Comparitive genomics Proteomics
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Genomics The study of genomes Subdivided into- Structural genomics: genome sequencing and  ID of genes and regulatory regions Functional genomics: Identify protein function Comparative genomics: comparison of  genomes 
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Goals of Genomics Compile sequence information Identify and annotate genes in genome Establish function of genes in genome Identify all proteins produced by genome Comparisons between genomes to study  relationships Catalogue sequence polymorphisms
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