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Courtroom DNA - The Case of the Druid Dracula Click to edit...

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Click to edit Master subtitle style 11 The Case of the Druid Dracula
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Learning Objectives 1. Make a diagram of a DNA molecule that accurately depicts the relationship and polarity of each DNA strand in the molecule. 2. Describe how cells replicate their DNA and predict how replication would be affected if one of the major enzymes involved was missing from the cell. 3. Compare and contrast DNA replication and Polymerase Chain Reaction (PCR) 4. Explain how gel electrophoresis is used to analyze DNA and analyze gel electrophoresis results to troubleshoot PCR reactions. 5. Explain how DNA can vary from one individual to the next and how these differences can be used to create a DNA “fingerprint.” Evaluate DNA fingerprint data. 22
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33 The Crime In a quiet corner of Wales in the village of Llanfairpwll, 90-year-old Mabel Leyshorn was murdered. Her murder had been not only brutal (her heart had been hacked out), but also creepy. It appeared as if Mabel’s blood had been collected in a small kitchen saucepan and tasted. The murder showed other signs of the occult: a candlestick and a pair of crossed pokers had been arranged near the body. - from BBC’s Crimewatch December 2001
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44 The Crime Scene Further investigation indicated that this was no supernatural villain at work: the murderer had worn tennis shoes which had left distinctive footprints under the glass door that had been shattered by a piece of broken garden slate. Moreover, the windowsill had bloodstains on it; with any luck, the evidence recovery unit hoped to use it to help determine who had committed the crime.
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55 What is your blood type? A. A B. B C. AB D. O E. Don’t know Clicker Question 1
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66 Evidence in the Courtroom Rape cases Paternity testing Historical/missing persons investigations Military “dog tag” Convicted felon databases Sources of DNA? Blood was previously used for blood typing Now used as a source of DNA Uses for DNA fingerprinting
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77 DNA in the Cell Target Gene chromosome double stranded DNA molecule individual nucleotides
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88 Clicker Question 2 Based on the figure below, rank these terms in order from largest to smallest.
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