BIO 202 Lecture 4

BIO 202 Lecture 4 - Macromolecules 2: Nucleic Acids...

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Macromolecules 2: Nucleic Acids
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Nucleotides FUNCTION AS: – Energy carriers (ATP, GTP) – Signals (cAMP) – Subunits of DNA & RNA Are of 5 kinds and belong to two groups: – Pyrimidines (6-membered ring) • Cytosine • Thymine • Uracil – Purines (5-membered ring attached to 6-membered ring) • Adenine • Guanine
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DNA and RNA structure Nitrogenous bases (building blocks of DNA and RNA) In RNA only
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Nucleosides • Base is at carbon 1 • Carbons 3 and 5 are functionally very important NUCLEOSIDE = BASE + SUGAR (ribose/deoxyribose) (5) (3) (1)
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In DNA, the sugar is DEOXYRIBOSE (lacks oxygen at position 2) In RNA, the sugar is RIBOSE (has oxygen at position 2) Thus, in DNA, the nucleosides are: •Deoxyadenosine •Deoxyguanosine •Deoxythymidine •Deoxycytidine In RNA, the nucleosides are: •Adenosine •Guanosine •Cytidine •Uridine
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and RNA • BASES: – Uracil vs. Thymine • Uracil lacks the methyl group at position 5 • SUGARS: – Ribose vs. Deoxyribose • Deoxyribose lacks oxygen at position 2
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This note was uploaded on 09/22/2011 for the course BIO 202 taught by Professor Dean during the Fall '08 term at SUNY Stony Brook.

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BIO 202 Lecture 4 - Macromolecules 2: Nucleic Acids...

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