LEcture 23 cell cycle

LEcture 23 cell cycle - Cell Cycle Regulation Campbell 6 th...

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Unformatted text preview: Cell Cycle Regulation Campbell 6 th ed: pp. 224-227 7 th ed: pp. 228-230 8 th ed: pp. 238-241 To get ahead: before next class check Fig. 13.7 (6 th ) or Fig. 13.8 (7 th & 8 th ed.) Cells don’t always divide. Even some bacteria can stop dividing if conditions are bad. They form inert spores until conditions improve. Multi-celled organisms : Many cells rarely divide in adults. Non-dividing cells remain in G0 phase. G1 S G2 G0 Cell cycle is highly regulated even in dividing cells. Experiment : fuse a cell in M with a cell in G1 Result: G1 cell enters M 2nd Experiment : fuse a cell in S with a cell in G1 Result: G1 cell enters S! Conclude : something in cytoplasm controls cell cycle. Cell in M or S had a signal. After fusion; cell in G1 got the signal - AT THE WRONG TIME! Proteins provide the signals. Hard to identify in human cells; easier in simple “model” systems (e.g. yeast). The SAME PROTEINS work in both cells! work in both cells!...
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This note was uploaded on 09/22/2011 for the course BIO 202 taught by Professor Dean during the Fall '08 term at SUNY Stony Brook.

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LEcture 23 cell cycle - Cell Cycle Regulation Campbell 6 th...

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