BIO370lec6

# BIO370lec6 - Lecture6 Populations II Equations P=G E VP =...

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Lecture 6 Populations II

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Equations P = G + E V P = V G + V E + 2Cov GE (if uncorrelated = 0) V G = V A + V D + V I (V n =V D + V I ; non-additive) H 2 = V G / V P (broad-sense) h 2 = V A / V P (narrow-sense) R = h 2 S (breeder’s equation, R=response, S=selection differential, also called selection coefficient (s) but this is used elsewhere) R/S = h 2 (realized heritability) R = Gß (ß = selection gradient) http://doublehelixranch.com/heritability.html See Chapter 9: 9.1, 9.3, 9.4, 9.5, Box, 9.4

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Population Genetics A population is a group of interbreeding individuals and their offspring Population genetics tracks the fate, across generations, of genes in populations Will a certain allele increase or decrease in frequency through time?

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G.W. Hardy & W. Weinberg (1908) Most geneticists naively thought that the most common allele would spread through a population Using algebra, they showed: In the absence of evolutionary processes, gene frequencies will stay the same through time
A gene pool – a population of sperm & egg 12 A (6 sperm, 6 eggs) 8 a (4 sperm, 4 eggs) 20 gene copies total p= freq. of A = 12/20= 0.6 q= freq. of a = 8/20 = 0.4 p + q = 1

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BIO370lec6 - Lecture6 Populations II Equations P=G E VP =...

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