9-7-11 - normal GOF LiCl LOF Gene expression circuits...

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Sea urchin fate map mesoderm fates are specified by 16 cells an 1 2 veg 1 2 : mostly endoderm micromeres: skeleton
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Regulative development in action Driesch 1893: potential is greater than fate Fig II-7
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Micromeres are responsible for the specification of endoderm
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Skeletogenic micromeres are autonomously specified Dev Bio toolkit: recombination (aka heterotopic transplantation)
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The canonical Wnt pathway pgs 92-93 mutation causes adenomatous polyposis of the colon
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β-catenin is the micromere determination factor
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Unformatted text preview: normal GOF: LiCl LOF Gene expression circuits double negative gate feed forward circuit repression activation Autonomous micromere specification The notch pathway p98 presenilin Non-autonomous specification of mesenchyme Sea urchin gastrulation infolding of cells inturning of cells migration of individual cells splitting 1 sheet into 2 expansion of 1 sheet of cells Convergent/ extension Sea urchin gastrulation Ingression Invagination convergent extension...
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This note was uploaded on 09/22/2011 for the course BIO 349 taught by Professor Wallingford during the Spring '09 term at University of Texas.

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9-7-11 - normal GOF LiCl LOF Gene expression circuits...

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