Presentation 11

Presentation 11 - Presentation 11 Figure 24.42 1...

Info iconThis preview shows pages 1–8. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Figure 24.42 Presentation 11
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 { { } } { { Presentation 28 Figure 24.1
Background image of page 2
3 Figure 24.7
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 Figure 24.3 Protein synthesis A site = acceptor site P site = peptidyl site E site = exit Figure 24.6
Background image of page 4
5 Initiation in Bacteria Needs 30S Subunits and Accessory Factors Initiation of protein synthesis requires separate 30S and 50S ribosome subunits. Initiation factors (IF-1, -2, and -3), which bind to 30S subunits, are also required. A 30S subunit carrying initiation factors binds to an initiation site on mRNA to form an initiation complex. Figure 24.10 Prokaryotic system
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
6 mRNA Binds a 30S Subunit to Create the Binding Site for a Complex of IF-2 and fMet-tRNAf An initiation site on bacterial mRNA consists of the AUG initiation codon preceded with a gap of ~10 bases by the Shine–Dalgarno polypurine hexamer. The rRNA of the 30S bacterial ribosomal subunit has a complementary sequence that base pairs with the Shine–Dalgarno sequence during initiation. Figure 24.12 Prokaryotic system
Background image of page 6
A Special Initiator tRNA Starts the Polypeptide Chain Translation starts with a methionine amino acid usually coded by AUG. In bacteria, different methionine tRNAs are involved in initiation and elongation. The initiator tRNA has unique structural features that distinguish it from all other tRNAs. fMet-tRNA
Background image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 8
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 09/25/2011 for the course GEN 409 taught by Professor Linda during the Spring '09 term at Iowa State.

Page1 / 36

Presentation 11 - Presentation 11 Figure 24.42 1...

This preview shows document pages 1 - 8. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online