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bio notes ch 44

bio notes ch 44 - bio

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Ascending loop of Henle Ascending limb permeable to salt, not H 2 O Thin segment NaCl leaves filtrate passively osmolarity of ISF of medulla Thick segment NaCl leaves filtrate actively (protein/energy/low to high) Loss of NaCl w/o loss of H 2 O osmolarity of filtrate as it moves up to cortex Distal Tubule = potassium K secretion + reabsorb NaCl + ph Key role in regulation of [K+] and [NaCl] : - varying amount of K+ secreted into filtrate / amount of NaCl reabsorbed from filtrate Like proximal tubule, distal tubule plays role in pH regulation o Controlled secretion of H+ o Reabsorption of HCO 3 Collecting Duct = concentration of urine Active reabsorption NaCl regulate [NaCl] in urine Permeable to H 2 O as filtrate traverses collecting duct [filtrate] as it loses H 2 O by osmosis to hyperosmotic ISF - - - excretion of hyperosmotic urine Inner medulla permeability to urea = osmolarity of ISF - - - excretion of hyperosmotic urine
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