Unformatted text preview: bold means principle reaction a strong base is usually a good nucleophile e.g. OH-and the alkoxide ions a strong base favours E1 strong nucleophile = -CN and S N 2: weak nucleophile = H 2 O and S N 1 S N 1 favoured by very polar solvents e.g. water S N 2 favoured by polar solvents that do not solvate the nucleophile High [Nü] or base favours S N 2 or E2 Low [Nü] favours S N 1 or E1...
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- Spring '11
- Nucleophilic substitution, Solvent