(f)A phenyl substituent is activating and ortho, para-directing. Biphenyl will undergo chlorina-tion readily.Each benzene ring of benzophenone is deactivated by the carbonyl group.Benzophenone is much less reactive than biphenyl in electrophilic aromatic substitutionreactions.12.25Reactivity toward electrophilic aromatic substitution increases with increasing number of electron-releasing substituents. Benzene, with no methyl substituents, is the least reactive, followed bytoluene, with one methyl group. 1,3,5-Trimethylbenzene, with three methyl substituents, is the mostreactive.o-Xylene and m-xylene are intermediate in reactivity between toluene and 1,3,5-trimethylben-zene. Of the two, m-xylene is more reactive than o-xylene because the activating effects of the two
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This note was uploaded on 09/26/2011 for the course CHM 2210 taught by Professor Reynolds during the Fall '01 term at University of Florida.