Dolbier HW Solutions 299

Dolbier HW Solutions 299 - 293 REACTIONS OF ARENES...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
position that is ortho to the chlorine puts it meta to the carboxyl and meta to the f rst nitro group. ( b ) An amino group is one of the strongest activating substituents. The para and both ortho posi- tions are readily substituted in aniline. When aniline is treated with excess bromine, 2,4,6- tribromoaniline is formed in quantitative yield. ( c ) The positions ortho and para to the amino group in o -aminoacetophenone are the ones most activated toward electrophilic aromatic substitution. ( d ) The carboxyl group in benzoic acid is meta-directing, and so nitration gives m -nitrobenzoic acid. The second nitration step introduces a nitro group meta to both the carboxyl group and the f rst nitro group. ( e ) Both bromine substituents are introduced ortho to the strongly activating hydroxyl group in
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 09/26/2011 for the course CHM 2210 taught by Professor Reynolds during the Fall '01 term at University of Florida.

Ask a homework question - tutors are online