NPB168-lecture2

NPB168-lecture2 - Pharmacology Pharmacokinetics - study of...

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Sheet1 Page 1 ÿþPharmacology Pharmacokinetics - study of movement of drugs through the body Kinetics - the course of a particular drug action onsent and duration Components: - route of administration -Oral ingested -> GI tract -Inhalation ->lungs ->alveoli -> highly vascularized ->very fast and effective -Injection ->Subcutaneous - under the skin -absorption rate depends on degree of local tissues ->Intramuscular - into the muscles -blood supply in muscles ->Intraveinous - into veins - fast and effective -Snort -> nasal passage ->passage well vascularized -rectally (suppository) ->well vascularized -transdermal ->ex. nicotine patch (oil) ->oil goes through the skin slowly -sublingual (under the tongue) ->ex. vitamin tablets
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Sheet1 Page 2 ->vascularized - absorption What does it have to go through to get into the blood plasma? unless it is injected IV, it has to cross the plasma membrane -can the drug cross this barrier? -is the drug lipophilic or hydrophilic
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NPB168-lecture2 - Pharmacology Pharmacokinetics - study of...

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