The starting materials for the mixed aldol condensation—benzaldehyde and propanal—areprepared by oxidation of benzyl alcohol and 1-propanol, respectively.(c)The cyclohexene ring in this case can be assembled by a Diels–Alder reaction.1,3-Butadiene is one of the given starting materials; the a,b-unsaturated ketone is the mixedaldol condensation product of 4-methylbenzaldehyde and acetophenone.The complete synthetic sequence isa,b-Unsaturated ketones are good dienophiles in Diels–Alder reactions.4-Methylbenzaldehyde
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This note was uploaded on 09/28/2011 for the course CHM 2210 taught by Professor Reynolds during the Fall '01 term at University of Florida.