Article+-+Wired+-+Your+Life+Decoded+Questions - 6 How does...

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Your Life Decoded article questions 1. Who are Linda Avey and Anne Wojcicki (what did they do in the article)? They were the people who started 23andMe. 2. On the company’s website, what can people do (aside from assess their risk for disease)? Give one example. They can uncover their heritage, or screen for a carrier status. 3. Regarding disease what does the article say is wrong with the Mendelian approach to the “a bad gene leads to a disease” relationship (called the “common disease, common gene hypothesis” in the article)? About 95% of diseases are not only linked to one gene, compared to the 5% that are. 4. What is an “SNP”? What is their significance? They are single nucleotide polymorphisms and we have millions of them in our DNA. They are most likely the cause for several diseases which is why they need to be studied. 5. Why doesn’t the main company discussed offer diagnostic testing for disease? It allows them not to be regulated by the FDA as they have strict regulations.
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Unformatted text preview: 6. How does the actual testing work (the stuff carried out by the company Illumina)? Illumina uses a large amount of nanoscopic dots, upwards of 500,000, with each detecting a different SNP. With that knowledge, researchers can determine your likelihood for diseases related to those specific SNPs. 7. What do the researchers expect to change in the next few years regarding the process and obtaining information? Wojcicki says that one day she hopes people will come together with similar genetic profiles and compare them and their notes about themselves, and others say that it is a matter of time before everyone knows what their genome has in store for them with respect to disease and the like. Yet researchers also believe that even if people know about a chance for disease they have, over half will not act on it. Maybe that will change in the future, but we cannot know now....
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This note was uploaded on 09/27/2011 for the course ECON 101 taught by Professor Johnsmith during the Spring '11 term at Emmanuel College.

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