1. Under anaerobic conditions, muscle cells can obtain ATP quickly from glycolysis. Subsequent lactic acid fermentation does not yield additional ATP. Explain whether it would be more efficient for muscle cells to oxidize glucose to pyruvate only instead of lactic acid. Under anaerobic conditions oxygen is not used as the final acceptor in the Electron Transport Chain. Lactic Acid Fermentation is used under these conditions oxygen-less conditions for ATP production. The lactate produced during Lactic Acid Fermentation from pyruvate eventually gets converted back into pyruvate. Without this conversion from pyruvate back to pyruvate, the process would be more efficient and straightforward with the final goal of ATP production. 2. Using your notes and the textbook, thoroughly explain the regulation of phosphofructokinase. Phosphofructokinase is large enzyme and an important allosteric regulator. As a regulator it adds a phosphate to fructose-6-phosphate creating fructose 1,6 biphosphate. The reaction that this allosteric enzyme catalyzes is very very exergonic and in turn
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This note was uploaded on 09/27/2011 for the course BIOL 101 taught by Professor Fevzidaldal during the Fall '08 term at UPenn.