Chapter_36 - Chapter 36 Defense Against Disease The Immune...

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Chapter 36 Defense Against Disease: The Immune System
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Three lines of defense against microbial attack
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Three lines of defense: 1: external barriers (skin, mucous membranes)
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Three lines of defense: A. skin
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Three lines of defense: external barriers A.skin physical barrier to microbial entry
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Three lines of defense: 1. external barriers A.skin physical barrier inhospitable environment for growth; dry, dead cells at surface. Sweat/sebaceous glands secreting acids & natural antibiotics like lactic acid.
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Three lines of defense: 1. external barriers A.skin physical barrier inhospitable environment B.mucous membranes of respiratory and digestive tracts well-defined. Secretions have antibacterial enzymes.
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Chapter 36 cont’d: Three lines of defense against microbial attack
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Dirt caught in mucus, moved by cilia
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Three lines of defense: 1. external barriers A.skin physical barrier inhospitable environment B.mucous membranes C.Stomach; if microbes swallowed, acids and protein-digesting enzymes destroy them
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Lines of defense: 2. nonspecific internal defense
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Lines of defense: 2. nonspecific internal defense A.phagocytic cells: white blood cells (WBC) in extracellular fluid, amoeboid shape, destroy microbes by phagocytosis.
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Lines of defense: 2. nonspecific internal defense A. phagocytic cells B. natural killer cells: WBC that destroy body cells infected by viruses and cancerous cells by punching HOLES in them.
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Lines of defense: 2. nonspecific internal defense A. phagocytic cells B. natural killer cells C. inflammatory response, caused by large-scale microbial invasion through wound
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Lines of defense: 2. nonspecific internal defense A. phagocytic cells B. natural killer cells C. inflammatory response histamine is released when cell damage is detected
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Lines of defense: 2. nonspecific internal defense A. phagocytic cells B. natural killer cells C. inflammatory response histamine increases blood flow to “wash” out wound
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