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Problem Set 1_2011 - Genetics 380 Spring 2011 Take-Home...

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Genetics 380 : Spring, 2011 Take-Home Problem Set #1 (Due the week of 1/24/2011) Chapter 1 1. Chemical analysis of the DNA of a virus from Mars reveals that it has 48% G, 48% C and 4% A. Suggest some possible structures for this DNA? 2. The sequence of a RNA transcript is 5'-GGUUACAUUC-3'. The sequence of the DNA template would be- A) 5'-GGUUACAUUC-3'. B) 5'-GAATGTAACC-3'. C) 5'-CCAATGTAAG-3'. D) 5'-CUUACAUUGG-3'. Use the genetic code table on p. 25 of the Hartl and Jones textbook for questions 3-4. 3. (a) Which amino acids have only 1 codon? (b) Which amino acid has 3 codons? (c) Which amino acids have 6 codons? (d) Which codons do not code for any amino acids? 4. The amino acid changes shown below have been observed in the α and β polypeptide chains of the human hemoglobin. The amino acids connected by lines are related by single nucleotide changes. Propose the most likely codon(s) for each of the amino acids.
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Chapter 2 5. The recognition sequences and the cutting sites within the recognized DNA sequence
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