Problem Set 5-1

Problem Set 5-1 - Genetics 380 : Spring, 2011 Take-Home...

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Take-Home Problem Set #5 Chapter 14 : Mutations 1 . The lysine codon AAA can be changed into 9 other codons by a single base (a) List the 9 mutant codons and the amino acids they code for. (b) Which of these changes would be considered silent mutations? 2 . Transposons can mediate intrachromosomal recombination- that is 2 transposable elements on the same chromosome can pair and recombine with each other. What would a recombination event produce if the transposon s were oriented in the same direction on the chromosome [see diagram (a) below]? What if they were oriented in opposite (inverse) orientations [see diagram (b) below]? Genetics 380 : Spring, 2011 (Due the week of 2/21) substitution mutation. Use the genetic code table in your book ( Table 1.1, p. 25 ). (c) Which ones are nonsense mutants? (d) Which of the 9 changes are transition mutations and which ones are transversion mutations?
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3 . Which of the following amino acid substitutions should you expect to be induced by the base analog mutagen 5-Bromouracil? Use the genetic code table in your book
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Problem Set 5-1 - Genetics 380 : Spring, 2011 Take-Home...

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