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Problem Set 13 - Genetics 380 Spring 2011 Problem Set...

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Problem Set 13 1. One of the maternal effect genes in Drosophila is called “bicoid”. It has no zygotic expression. Recessive mutations in bicoid (bcd) cause embryonic death by preventing the formation of anterior structures. Predict the phenotypes of- (a) bcd/bcd homozygous recessive animals produced by mating +/bcd males and females. (b) bcd/bcd animals produced by mating bcd/bcd females with bcd/+ males. (c) +/bcd animals produced by mating bcd/bcd females with bcd/+ males. (d) bcd/bcd nimals produced by mating +/bcd females with bcd/bcd males. (e) +/bcd animals produced by mating +/bcd females with bcd/bcd males. 2. A C. elegans contig for one region of chromosome II is as follows, where A through H are cosmids carrying pieces of C. elegans genomic DNA: a . A cloned gene X hybridizes to cosmids C, D, and E. What is the approximate location of this gene X on the chromosome? b . A cloned gene Y hybridizes only to cosmids E and F. What is its location?
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Problem Set 13 - Genetics 380 Spring 2011 Problem Set...

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