Problem Set 1 Answer

Problem Set 1 Answer - Genetics 380 : Spring, 2011...

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Answer Sheet 1. Since the DNA is lacking thymines, no A:T base pairs are possible. Therefore, this DNA cannot be a normal double stranded DNA. It may be- a. Single-stranded DNA. b. Since G and C are 48% each, it may be mostly double-stranded with G:C base pairing and the 4% residues that are adenines would be left unpaired. The adenines could all be at the ends (one or both; attached to only one strand or both strands) or they may be interspersed with fully double-stranded DNA (in that case the A-residues would loop out of the helix). 2. RNA is copied from DNA in anti-parallel orientation and in the 5’-> 3’ direction. Therefore, the DNA-RNA hybrid would look like- RNA strand 5'-GGUUACAUUC-3' DNA template strand 3’-CCAATGTAAG-5’ The correct answer is (b) 5'-GAATGTAACC-3' 3. a . Met (AUG), Trp (UGG) b. Ile (AUU, AUC, AUA) c . Leu (UUA,UUG, CUU, CUC, CUA, CUG), Arg (CGU, CGC, CGA, CGG, AGA, AGG) and Ser (UCU, UCC, UCA, UCG, AGU, AGC) d . UAG (amber), UAA (ochre) and
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Problem Set 1 Answer - Genetics 380 : Spring, 2011...

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