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Unformatted text preview: deletion in the second codon (UUC-> UC). This changed the reading frame from the 2 nd codon to the end of the protein resulting in a defective protein. The second mutation was an addition of a nucleotide at the end of the 5th codon (GUG AUU ->either GU N GAU or GUG G AU). This restored the reading frame so that the protein was normal after the 5th amino acid. From the data it cannot be determined whether the deletion (-U ) or the addition ( +N or +G ) occurred first (see next page for details)-...
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This note was uploaded on 09/29/2011 for the course GENETICS 380 taught by Professor Glodowski during the Spring '08 term at Rutgers.
- Spring '08