Dolbier HW Solutions 421

Dolbier HW Solutions 421 - 515 CARBOXYLIC ACIDS(b...

Info iconThis preview shows page 1. Sign up to view the full content.

View Full Document Right Arrow Icon
( b ) Formaldehyde can serve as a one-carbon source if it is attacked by the Grignard reagent de- rived from bromobenzene. This sequence yields 14 C-labeled benzyl alcohol, which can be oxidized to 14 C-labeled benzoic acid. ( c ) A direct route to 14 C-labeled benzoic acid utilizes a Grignard synthesis employing 14 C-labeled carbon dioxide. 19.19 ( a ) An acid base reaction takes place when pentanoic acid is combined with sodium hydroxide. ( b ) Carboxylic acids react with sodium bicarbonate to give carbonic acid, which dissociates to carbon dioxide and water, so that the actual reaction that takes place is ( c ) Thionyl chloride is a reagent that converts carboxylic acids to the corresponding acyl chlorides. ( d ) Phosphorus tribromide is used to convert carboxylic acids to their acyl bromides. Pentanoic acid 3CH 3 CH 2 CH 2 CH 2 CO 2 H Phosphorus tribromide PBr 3 Phosphorus acid H 3 PO 3 11 Pentanoyl bromide 3CH 3 CH 2
Background image of page 1
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Ask a homework question - tutors are online