Dolbier HW Solutions 453

Dolbier HW Solutions 453 - 547 CARBOXYLIC ACID DERIVATIVES:...

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Step 2: Nucleophilic addition of water Step 3: Deprotonation of oxonium ion to give neutral form of tetrahedral intermediate Step 4: Protonation of amino group of tetrahedral intermediate Step 5: Dissociation of N -protonated form of tetrahedral intermediate Step 6: Proton-transfer processes 11 HO H H 1 Hydronium ion O H H Water Protonated form of acetic acid OH CH 3 C OH 1 O CH 3 C OH Acetic acid H 2 NC 6 H 5 Aniline H 3 NC 6 H 5 Anilinium ion Hydronium ion O 1 H H H Water O H H 1 N -Protonated form of tetrahedral intermediate CH 3 C OH NC 6 H 5 OH H H 1 1 OH CH 3 C OH 1 Protonated form of acetic acid H 2 NC 6 H 5 Aniline
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