(l)The starting material is a cyclic ester, a lactone. Esters undergo saponifcation in aqueous baseto give an alcohol and a carboxylate salt.(m)Ammonia reacts with esters to give an amide and an alcohol.(n)Lithium aluminum hydride reduces esters to two alcohols; the one derived from the acyl groupis a primary alcohol. Reduction of a cyclic ester gives a diol.(o)Grignard reagents react with esters to give tertiary alcohols.(p)In this reaction methylamine acts as a nucleophile toward the carbonyl group of the ester. Theproduct is an amide.(q)The starting material is a lactam, a cyclic amide. Amides are hydrolyzed in base to amines andcarboxylate salts.1SodiumhydroxideNaOHSodium 4-(methylamino)butanoate
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This note was uploaded on 09/30/2011 for the course CHM 2210 taught by Professor Reynolds during the Fall '01 term at University of Florida.