9700_w08_qp_4 - UNIVERSITY OF CAMBRIDGE INTERNATIONAL...

Info iconThis preview shows pages 1–6. Sign up to view the full content.

View Full Document Right Arrow Icon
This document consists of 20 printed pages, 2 lined pages and 2 blank pages. SPA (DR/DR) T62741/3 © UCLES 2008 [Turn over UNIVERSITY OF CAMBRIDGE INTERNATIONAL EXAMINATIONS General Certificate of Education Advanced Level READ THESE INSTRUCTIONS FIRST Write your Centre number, candidate number and name in the spaces provided at the top of this page. Write in dark blue or black pen. Do not use staples, paper clips, highlighters, glue or correction fluid. DO NOT WRITE IN ANY BARCODES. Section A Answer all questions. Section B Answer one question. Circle the number of the Section B question you have answered in the grid below. At the end of the examination, fasten all your work securely together. The number of marks is given in brackets [ ] at the end of each question or part question. BIOLOGY 9700/04 Paper 4 Structured Questions A2 Core October/November 2008 2 hours Candidates answer on the Question Paper. No Additional Materials are required. For Examiner’s Use 1 2 3 4 5 6 7 8 9 Section B 10 or 11 Total
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 9700/04/O/N/08 For Examiner’s Use © UCLES 2008 Section A Answer all the questions. 1 The African hunting dog, Lycaon pictus , is a carnivore which hunts in packs in areas of East Africa. Fig. 1.1 shows an African hunting dog. Fig. 1.1 (a) The African hunting dog has cells that are eukaryotic while bacteria have cells that are prokaryotic. Describe the differences between eukaryotic and prokaryotic cells with respect to their DNA . .......................................................................................................................................... .......................................................................................................................................... ...................................................................................................................................... [2]
Background image of page 2
3 9700/04/O/N/08 [Turn over For Examiner’s Use © UCLES 2008 (b) In some parts of East Africa L. pictus is becoming an endangered species. Suggest reasons why L. pictus is becoming an endangered species. .......................................................................................................................................... .......................................................................................................................................... .......................................................................................................................................... .......................................................................................................................................... .......................................................................................................................................... .......................................................................................................................................... .......................................................................................................................................... ...................................................................................................................................... [3] (c) One way of protecting L. pictus is to create conservation areas. Describe two other methods of conserving endangered species such as L. pictus . .......................................................................................................................................... .......................................................................................................................................... ...................................................................................................................................... [2] [Total: 7]
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
4 9700/04/O/N/08 For Examiner’s Use © UCLES 2008 2 Fig. 2.1 shows the CFTR (cystic fibrosis transmembrane conductance regulator) protein in a plasma (cell surface) membrane. Fig. 2.1 (a) (i) Describe the normal function of the CFTR protein. .................................................................................................................................. .................................................................................................................................. .............................................................................................................................. [2] (ii) On Fig. 2.1, use the letter E to indicate the external face of the membrane. State how you identified this face. .................................................................................................................................. .............................................................................................................................. [1] (b) Cystic fibrosis is caused by a recessive allele of the CFTR gene. (i) Explain the meaning of the term recessive allele . .................................................................................................................................. .................................................................................................................................. .............................................................................................................................. [2]
Background image of page 4
5 9700/04/O/N/08 [Turn over For Examiner’s Use © UCLES 2008 (ii) Explain how cystic fibrosis affects the function of the lungs. .................................................................................................................................. .................................................................................................................................. .................................................................................................................................. .................................................................................................................................. .............................................................................................................................. [3] (c) As cystic fibrosis is caused by a recessive allele of a single gene, it is a good candidate for gene therapy. Trials were undertaken in the 1990s, attempting to deliver the normal allele of the CFTR gene into cells of the respiratory tract, using viruses or liposomes as vectors.
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 6
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 24

9700_w08_qp_4 - UNIVERSITY OF CAMBRIDGE INTERNATIONAL...

This preview shows document pages 1 - 6. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online