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Unformatted text preview: ORF: open reading frames, able to determine where genes are present in genome. 5 questions addressed: 1. How complex are living system? a. Very complex. b. Thousands of genes, thousands of proteins or RNA c. Human has 3.2*10^9 billion base pairs. 2. What is the simplest living system? a. Microplasma-500 genes b. .6 megabases, 600,000 nucleotides 3. Relationship btwn sixe of genome and complexity of organism. a. Appears maybe yes, but there are exceptions 4. Correlation btwn # of genes in genome and complexity of organism. a. Appears yes, but there are anomalies 5. Correlation btwn % of DNA that does not encode for protein or RNA and complexity. a. Non-coding DNA increases in genome as complexity increases. 2 mysteries that arise from study of genomes: 1. How can simple animals and humans have same # of genes? Human Vs. Chimps 99% o Total # RNA molecules transcribed 2. What is non-coding DNA doing?? Transcription: 120,000 different mRNAs...
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