2011 Graded Potentials and Neuromuscular Transmission

2011 Graded Potentials and Neuromuscular Transmission - Dr...

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C -64 Dr. Kennon M. Garrett GRADED POTENTIALS AND NEUROMUSCULAR TRANSMISSION Reading: Widmaier et al., Vander’s Human Physiology, 12th ed. pp. 147-149, 259-261. Behavioral Objectives 1. List the characteristics of graded potentials and list examples of graded potentials. 2. Compare and contrast the properties of action potentials and graded potentials. 3. List the events of neurotransmitter release. 4. List the events of neurotransmission at the neuromuscular junction and describe how action potentials are generated in skeletal muscle. I. Graded potentials - local changes in membrane potential A. Function – graded potentials are electrical signals that spread over a short distance. Their main purpose is to generate action potentials. B. Characteristics 1. Local currents (Fig. 6-15) , currents are generated only at the site of activation and are limited to the surrounding area of the membrane.
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