2011 Graded Potentials and Neuromuscular Transmission

2011 Graded Potentials and Neuromuscular Transmission - C -...

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Unformatted text preview: C - 64Dr. Kennon M. Garrett GRADED POTENTIALS AND NEUROMUSCULAR TRANSMISSIONReading: Widmaier et al., Vander’s Human Physiology, 12th ed. pp. 147-149, 259-261. Behavioral Objectives 1. List the characteristics of graded potentials and list examples of graded potentials. 2. Compare and contrast the properties of action potentials and graded potentials. 3. List the events of neurotransmitter release. 4. List the events of neurotransmission at the neuromuscular junction and describe how action potentials are generated in skeletal muscle. I. Graded potentials - local changes in membrane potentialA. Function – graded potentials are electrical signals that spread over a short distance. Their main purpose is to generate action potentials. B. Characteristics 1. Local currents(Fig. 6-15) , currents are generated only at the site of activation and are limited to the surrounding area of the membrane. C - 652. Vary in size- the amplitude of the potential is dependent on strength of stimulus, thus the term “graded potential”. 3. Depolarizing or hyperpolarizing(Fig. 6-16), The type of ion producing the graded potential will determine whether it is depolarizing or hyperpolarizing. 4. Summation- multiple graded potentials can occur and add together to produce a potential of greater amplitude than a single graded potential. a. Temporal – high frequencies of action potentials can produce repetitive stimuli that can summate into a large potential. C - 66b. Spatial – multiple inputs firing simultaneously can summate and produce a large potential. 5. Decremental - amplitude decreases with increasing distance from site of stimulus Graded potentials do not propagate....
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This note was uploaded on 10/01/2011 for the course PSYO 5016 taught by Professor Staff during the Fall '11 term at The University of Oklahoma.

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2011 Graded Potentials and Neuromuscular Transmission - C -...

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