2011 Male Reproductive Physiology

2011 Male Reproductive Physiology - E-91 Dr. Kennon Garrett...

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Unformatted text preview: E-91 Dr. Kennon Garrett MALE REPRODUCTIVE PHYSIOLOGY Reading: Vander et al., Human Physiology, 12 th ed. pp. 587-602. Behavioral Objectives 1. List the steps in mitosis and meiosis. Know when the mitosis and meiosis occurs in males and females. 2. List anatomical structures of the male reproduction system and list their functions. 3. List the steps in spermatogenesis. 4. List the functions of Sertoli and Leydig cells. 5. List steps involved in erection, emission and ejaculation and know how the parasympathetic and sympathetic nervous systems control these processes. 6. Describe the function of the hormones in the male reproduction system and describe how their release is regulated. I. Introduction A. Reproductive Organs 1. Testes 2. Ovaries E-92 B. Functions of gonads 1. Produce germ cells 2. Secrete sex steroids C. Accessory reproductive organs ducts and glands emptying into the ducts the used to transport sperm and eggs from gonads D. The reproductive axis (Fig. 17-1) 1. Hypothalamus - neurons release Gonadotropin Releasing Hormone (GnRH) in bursts. 2. Anterior pituitary releases gonadotropins FSH and LH. 3. Gonads - gonadotropins have 2 actions at gonads a. gametogenesis b. release steroid sex hormones. E-93 4. Sex steroids and inhibin exert feedback on the pituitary and hypothalamus. a. Sex steroids inhibit secretion of GnRH from hypothalamus b. Inhibit release of LH (via sex steroids) and FSH (via inhibin) from anterior pituitary II. Gametogenesis differentiation and development of germ cells into gametes A. Germ cells developing gametes 2 steps in gametogenesis 1) proliferation of primordial germ cells 2) differentiation into gametes B. Mitosis - proliferation of germ cells In females proliferation of germ cells by mitosis occurs entirely during embryological development. In males proliferation of germ cells by mitosis occurs in embryo and again starting at puberty and throughout life to supply sperm. 23 pair of chromosomes in humans (diploid) a. DNA replication - produces sister chromatids (tetraploid) b. Chromatids condense and become attached to spindle fibers c. Sister chromatids separate at centromere and each moves toward opposite poles d. Cell begins to constrict and cell pinches in half to form 2 cells Diploid Diploid Tetraploid E-94 C. Meiosis (Fig. 17-2) - produces gametes with single copy of 23 chromosomes (haploid). (Fig....
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This note was uploaded on 10/01/2011 for the course PSYO 5016 taught by Professor Staff during the Fall '11 term at The University of Oklahoma.

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2011 Male Reproductive Physiology - E-91 Dr. Kennon Garrett...

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