Absorption of Fluid and Electrolytes

Absorption of Fluid and Electrolytes - Dr. Kennon M....

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Unformatted text preview: Dr. Kennon M. Garrett GI-51 ABSORPTION OF FLUID AND ELECTROLYTES Learning Objectives 1. Describe the mechanism for absorption of sodium, chloride and potassium. 2. Describe the mechanism for absorption of calcium and its regulation by vitamin D. 3. Describe the mechanism for absorption of iron. 4. Describe the mechanism for absorption of water. Dr. Kennon M. Garrett GI-52 I. Fluid and electrolyte balance Source of ingested or secreted fluid Liter/day Absorbed fluid Liter/day Food and Drink 1.2 Small intestine 6.7 Saliva 1.5 Gastric juice 2.0 Colon 1.4 Pancreatic juice 1.5 Bile 0.5 Small Intestine 1.5 Total 8.2 Excreted 0.1 Major electrolytes (ingested and secreted): sodium, chloride, potassium, hydrogen and bicarbonate. II Intestinal absorption of major electrolytes A. Sodium and Chloride (NaCl) The intracellular concentration of Na + is maintained at a low level by activity of the Na/K ATPase which transports Na + out of the cell in exchange for K + . Na + moves "downhill" across the brush border membrane into the cell. Na + is then transported "uphill" across the basolateral membrane by the Na/K ATPase. Cl- is absorbed "downhill" in response to the potential difference generated by absorption of Na. is absorbed "downhill" in response to the potential difference generated by absorption of Na....
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Absorption of Fluid and Electrolytes - Dr. Kennon M....

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