A-4.The carboxypeptidase-catalyzed hydrolysis of a pentapeptide yielded phenylalanine (Phe).One cycle of an Edman degradation gave a derivative of leucine (Leu). Partial hydrolysisyielded the fragments Leu-Val-Gly and Gly-Ala among others. Deduce the structure of thepeptide.A-5.Consider the following compound:(a)What kind of peptide does this structure represent? (For example, dipeptide)(b)How many peptide bonds are present?(c)Give the name for the N-terminal amino acid.(d)Give the name for the C-terminal amino acid.(e)Using three-letter abbreviations, write the sequence.A-6.Consider the tetrapeptide Ala-Gly-Phe-Leu. What are the products obtained from each of thefollowing? Be sure to account for all the amino acids of the peptide.(a)Treatment with 1-fuoro-2,4-dinitrobenzene followed by hydrolysis in concentratedHCl at 100°C.(b)Treatment with chymotrypsin.(c)Treatment with carboxypeptidase(d)Reaction with benzyloxycarbonyl chloridePART BB-1.Which phrase correctly completes the statement?Except for glycine, which is achiral, all the amino acids present in proteins
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This note was uploaded on 10/03/2011 for the course CHM 2210 taught by Professor Reynolds during the Fall '01 term at University of Florida.