PHYSIOLOGY FINAL EXAM REVIEW.doc - BIOL 2204 Human...

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BIOL 2204 Human Physiology for NursingCumulative Final Exam’s Study Guide (Winter 2019)Section 1 (matching; 12 pts.) will cover Chapter 10 (based on the material covered in lecture and the assigned textbook pages).Be able to list and explain the events at the neuromuscular junction.
6.ACh broken down in synaptic cleft by acetylcholinesterase, diffused away from the junction, terminatingACh’s effects.Be able to list and explain the events of the excitation-contraction coupling process.
4.Myosin (thick muscle) binds to exposed binding sites on thin filaments (actin). Cross-bridge cycle results in muscle contraction (shortening)Be able to list and explain the events of a cross-bridge cycle. 1.Cross-bridge formation – myosin head binds to thin filament (actin)2.Power stroke – myosin head pivots and pulls actin towards the m-line/centre of the sarcomere3.Cross-bridge detachment – ATP attaches to myosin head, cross-bridge detaches4.Cocking of myosin head – ATP hydrolysed to ADP and inorganic phosphate, energy from hydrolysis cocks myosin head into high energy state
Section 5 (short answer; 12 pts.) will cover only selected topicsfrom Chapters 19, 20, 22, 23, 25 & 27 (based on the material covered in lecture and the assigned textbook pages), as follows:Topics for Chapter 19Be able to list and explain all the major events that occur at eitherone of the three phases of the cardiac cycle. {If this question is included in the exam, you will be asked to answer it for one of thephases of the cardiac cycle. To earn full points, you need to include in your explanation the ECG wave (depolarization or repolarization event), chambers’ relaxation or contraction state, chambers’ pressure, valves closure/opening, ventricular volume)Three phases of the cardiac cycle1.Ventricular filling (mid to late diastole)a.Semilunar valves are closed; atrioventricular valves are openb.Heart blood pressure is low; blood enters atria and flows into ventriclesc.Atria contracting, ventricles relaxedd.Atrial systole occurs, which completes ventricular fillinge.Sinoatrial node depolarizesf.

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