Chapter12_pt1_1slideperpg.pdf - Chapter 12(part 1 Basic Principles of Neurophysiology(pgs 523-530 I Membrane Potentials A Voltage Current Resistance and

Chapter12_pt1_1slideperpg.pdf - Chapter 12(part 1 Basic...

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Chapter 12 (part 1): Basic Principles of Neurophysiology (pgs. 523-530) I. Membrane Potentials A. Voltage, Current, Resistance, and the Ohm’s Law II. The Resting Membrane Potential (RMP) III. Different Membrane Ion Channels IV. Membrane Potentials as Signals A. Action Potentials (APs) B. Generation of an Action Potential
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Voltage, Current, Resistance, and the Ohm’s Law Voltage (in Volts (V) or Millivolts (mV)) is a measure of potential energy generated by separated charge between two points Current is flow of electrical charge (ions) between two points Resistance is hindrance to charge flow Ohm’s Law gives relationship of voltage, current, resistance Current (I) = voltage (V) / resistance (R) Hence: Current is directly proportional to voltage There is NO net current flow between points with same potential Current is inversely related to resistance
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Resting Membrane Potential The potential difference (–70 mV) across the membrane of a resting neuron It is generated by different concentrations of Na + , K + , Cl & protein anions (A
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