ANP Lec 3 - 2.3.1 Describe the microscopic structure of...

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2.3.1 Describe the microscopic structure of skeletal muscle fibers and explain the cellular mechanisms of excitation-contraction (pp. 275-289) 2.3.2 Describe the neuromuscular junction (pp. 285-289) 2.3.3 Describe the contractile properties of skeletal muscle (motor unit, isotonic & isometric contractions, spatial & temporal summation, etc) (pp. 289-297) 2.3.4 Associate various muscle types with their metabolism and their speed of contraction and rate of fatigue (pp. 296-305) 2.3.5 Compare the properties of smooth muscle with those of skeletal muscle (pp. 305-311)
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2.3.1.1 In table form, compare and contrast skeletal, smooth and cardiac muscle Common Features of Muscle Cells elongated cells = muscle fibers ; terminology: myo -, sarco -” muscle contraction depends on actin & myosin myofilaments Cardiac Muscle Skeletal Muscle Smooth Muscle Only in heart Striated, involuntary Pacemaker sets rate of contraction; neural input can increase rate bony skeleton Longest muscle fibers Striated, voluntary Can contract rapidly; rest Strong, adaptable Walls of hollow, visceral organs Nonstriated, involuntary Slow, sustained contractions J. Carnegie, UofO
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Muscle Functions 1. Generate movement: locomotion, manipulation, blood flow & pressure, respiration, propelling of food, urine, etc. . 2. Maintain posture: constantly working against gravity 3. Joint stabilization: eg: shoulders, knees when moving parts of skeleton 4. Generation of heat: maintenance of body temperature esp: skeletal muscle (at least 40% of body mass) Functional Characteristics of Muscle 1. Excitability (Irritability): ability to receive and respond to a stimulus” stimulus usually a chemical (NT, hormone, pH) response = AP along sarcolemma + muscle contraction 1. Contractility: “ability to shorten forcibly when adequately stimulated” 2. Extensibility: “ability to be stretched or extended” 4. Elasticity: “ability to resume resting length after being stretched” 2.3.1.2 list & briefly describe 4 muscle functions as well as 4 2.3.1.2 list & briefly describe 4 muscle functions as well as 4 functional characteristics of muscle functional characteristics of muscle J. Carnegie, U of O
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describe the anatomy of a skeletal muscle cell; define sarcolemma, sarcoplasm, myoglobin, myofibril, sarcoplasmic 2.3.1.4 differentiate between endomysium, perimysium and epimysium MICROSCOPIC ANATOMY OF A SKELETAL MUSCLE FIBER long, cylindrical cell with many oval nuclei ( where? What is the sarcolemma ?) muscle cell is said to be a syncytium - what does this mean?? sarcoplasm contains lots of glycogen & myoglobin - what is myoglobin?? lots of
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This note was uploaded on 10/03/2011 for the course ANP 1105 taught by Professor Carnegie during the Spring '08 term at University of Ottawa.

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ANP Lec 3 - 2.3.1 Describe the microscopic structure of...

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