Test 3 Spring 2009 Key - Thus, humans avoid the toxicity....

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MIBO3500 Sp 2009 exam 3 answers 1. D 2. D 3. A 4. B 5. D 6. C 7. A 8. D 9. B 10. C 11. B 12. A 13. A 14. B 15. B 16. C 17. A 18. C 19. A 20. C 21. A 22. D 23. A 24. A 25. C 26. K 27. G 28. C 29. J 30. R 31. B/S 32. A 33. I 34. H 35. L 36. J 37. L 38. M 39. P 40. F 41. R 42. H 43. A 44. N 45. D 46. A) Blocks folic acid synthesis (DNA synthesis, chromosome replication) B) Both bacteria and human pathways are blocked by the anti-metabolite, but humans have a mechanism to take folic acid up from their diet while bacteria do not.
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Unformatted text preview: Thus, humans avoid the toxicity. 47. Various mechanisms including development of enzymes that degrade antibiotics before they can have an effect on cells, changes in membrane permeability (efflux) of antibiotics from the cell, changes in binding targets (i.e. RNA polymerase, ribosome subunits) and others....
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