Exam2_fall2010 - GENE 3200 Fall 2010 Bedell Exam 2 Oct 7 ID no 810 Write your ID number(810 number NOT SSN on every page Write your initials on the

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GENE 3200 – Fall 2010 – Bedell Exam 2 – Oct 7 ID no. 810_____________________________ 1 Write your ID number (810 number, NOT SSN) on every page. Write your initials on the first page only. All of the multiple choice questions have only one correct answer. The exam should be completed in ink. Regrades will not be given if you write in pencil. All requests to re-grade an exam must be made in writing to Dr. Bedell within 48 hours of the grades being posted on WebCT. 1. The best football players have dominant alleles for three genes: big (B), smart (D), and fast (F). Recessive alleles for each of these genes result in being small (b), dumb (d), and slow (f). Data from a (hypothetical) three-pt testcross are shown below. Phenotype Genotype Number Big, smart, fast B, D, F 324 Small, smart, fast b, D, F 49 Big, dumb, fast B, d, F 3 Big, smart, slow B, D, f 42 Small, dumb, fast b, d, F 32 Small, smart, slow b, D, f 5 Big, dumb , slow B, d, f 51 Small, dumb, slow b, d, f 309 Total: 815 1A. (2 pts) What is the order of the three genes? Give a brief explanation for your answer. 1B. (6 pts) What are the distances in map units between the three genes? Show your calculations. 1C. (2 pts) How much crossover interference (if any) occurred? Show your calculations.
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GENE 3200 – Fall 2010 – Bedell Exam 2 – Oct 7 ID no. 810_____________________________ 2 2. (2 pts) In Griffith's transformation experiments the mice die when they were injected with which of the following kinds of bacteria? (a) heat-killed, S strain (b) live, R strain (c) live, R strain + heat-killed, S strain (d) heat-killed, R strain (e) live, R strain plus heat-killed, R- strain 3. (2 pts) What is the name of the structure to the right? (a) Alanine (b) Uracil (c) Adenine (d) Guanine (e) Methionine 3B. (2 pts) Number the positions of the carbon and nitrogen atoms in the structure above. 3C. (1 pt) Circle clearly the position where the pentose sugar would be added to this structure. 3D. (1 pt) True or false. Once the sugar is added to this structure, it's called a nucleoside. 4. When Meselson and Stahl performed their experiments to determine the mechanism of DNA replication, they grew cultures of E. coli in media containing a heavy isotope of nitrogen, then transferred cultures to media containing a light isotope of nitrogen and allowed the cultures to grow in the latter for one or two generations. The DNA from each culture was then subjected to density gradient ultracentrifugation in a solution of CsCl. 4. (cont) The possible results of their experiments are shown in the three panels (A, B, and C) to the right, with dashed horizontal lines indicating the positions of DNA after centrifugation ( 14 N/ 14 N, 14 N/ 15 N, and 15 N/ 15 N. 4A. (2 pts)
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This note was uploaded on 10/05/2011 for the course GENE 3200 taught by Professor Condie during the Fall '08 term at University of Georgia Athens.

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Exam2_fall2010 - GENE 3200 Fall 2010 Bedell Exam 2 Oct 7 ID no 810 Write your ID number(810 number NOT SSN on every page Write your initials on the

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