Final_Fall2010_ThursPM

Final_Fall2010_ThursPM - GENE3200 Fall 2010 Bedell Final...

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GENE3200 – Fall 2010 – Bedell Final Exam – Dec 9 ID no. 810 ________________________________ 1 Write your ID number (810 number, NOT SSN) on every page. Write your initials on the first page only. All of the multiple choice questions have only one correct answer. 1. In humans there are three unlinked genes that express antigens on the surface of red blood cells and determine different blood types. The I gene has three alleles ( I A , I B and i ) that determine the ABO blood group system. I A and I B are codominant, and both I A and I B are completely dominant to i . The MN gene has two codominant alleles ( M and N ) that determine blood type M, N, or MN. The Rh gene has two alleles [ positive ( pos ) and negative ( neg )], with the pos allele completely dominant to the neg allele. 1 . (cont) (3 pts) A woman with “O MN Rh pos” blood type has a child with “O N Rh neg” blood type. Of the following males, which is the biological father? Assume no involvement of the Bombay phenotype. (a) A M Rh pos (b) B MN Rh neg (c) O M Rh neg (d) AB MN Rh pos (e) None of the above 2. Somatic cells of domestic cats contain 38 chromosomes. 2A. (1 pt) In cats, how many chromosomes per cell are present at prophase of mitosis? 2B. (1 pt) In cats, how many chromatids per cell are present at prophase of mitosis? 2C. (1 pt) In cats, how many chromosomes per cell are present after the completion of meiosis II (including cytokinesis)? 3. (2 pts) The centromeres of sister chromatids uncouple and chromatids separate in which meiotic phase? (a) prophase I (b) prophase II (c) anaphase I (d) anaphase II 4. (1 pt) True or false. Centrosomes are the microtubule organizing centers at the spindle poles of cells in M phase. 5. (1 pt) True or false. The correct order of the five substages of meiotic prophase I is leptotene, zygotene, pachytene, diplotene, diakinesis. 6. (2 pts) Which of the following occurs during mitosis but does not occur during meiosis? (a) Segregation of sister chromatids. (b) Pairing of homologous chromosomes. (c) Crossing-over between homologous chromosomes. (d) Alignment of chromosomes on the metaphase plate. (e) None of the choices are correct. 7. (1 pt) True or false. Crossing over between homologous chromosomes during prophase I of meiosis is the aspect of chromosome behavior that most clearly accounts for Mendel's 2 nd law. 8. (1 pt) True or false. During initiation of DNA replication, primase is the enzyme that unwinds the double helix to separate the parental strands of DNA.
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GENE3200 – Fall 2010 – Bedell Final Exam – Dec 9 ID no. 810 ________________________________ 2 9. (2 pts) DNA polymerase catalyzes the formation of a bond between the ____________. (a)
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Final_Fall2010_ThursPM - GENE3200 Fall 2010 Bedell Final...

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