bio lecture 4. cell structure

bio lecture 4. cell structure - Cell Structure Dr Mark...

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8/27/2011 1 Cell Structure Dr. Mark Holbrook Cell Structure • Some methods used to study cells • Structure and function of organelles • Cytoskeleton Cells Uni cellular Multi cellular All organisms are made of cells
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8/27/2011 2 How are cells visualized? • Cells and especially their components are too small to be seen by the human eye (cells < 0.1mm) • Biologists use microscopes to enlarge images of cells From Micrographia , published in 1665 by Robert Hooke Light Microscopy Phase- contrast Bright field (unstained) Bright field (stained) cheek epithelial cells Differential Interference Contrast (Nomarsky)
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8/27/2011 3 Nomarsky in C. elegans development Fluorescent Labels From UCLA BRAIN RESEARCH INSTITUTE MICROSCOPY CORE FACILITIES Distinguish structures within a cell Fluorescent Labels Jean Livet et al 2007, Nature (450) “Brainbow” mouse : distinguish specific brain cells Distinguish cells from one another
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8/27/2011 4 Electron Microscopy SEM TEM Prokaryotes vs. Eukaryotes
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This note was uploaded on 10/11/2011 for the course BIO 010 taught by Professor Holbrook during the Spring '11 term at Iowa State.

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bio lecture 4. cell structure - Cell Structure Dr Mark...

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