bio lecture 8. replication

bio lecture 8. replication - Replication Mark Holbrook Base...

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1 Replication Mark Holbrook Base Pairing Allows Replication Complementary pairing of the bases in the double helix model suggested the mechanism of self-replication. After strand separation, a base on one strand determines the opposing base on the other strand. Each strand thus serves as a template for the synthesis of a complementary strand. A DNA molecule A Model for DNA Replication: Basic Concept 16.9
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2 After separation, each parental strand becomes a template A Model for DNA Replication: Basic Concept 16.9 The nucleotide sequence of the parent molecule determines the sequence of the daughter molecule. Replication is semiconservative : Each “daughter” molecule has one and one new strand . A Model for DNA Replication: Basic Concept DNA synthesis results in two copies of the original molecule 16.9 parental strand 16-10 Parent cell First replication Second replication (a) Conservative model (b) Semiconserva- tive model (c) Dispersive model all parental “hybrid” mixture Replication Models “hybrid” “hybrid” all new all parental
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3 16- 11a EXPERIMENT
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bio lecture 8. replication - Replication Mark Holbrook Base...

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