bio lecture 9.transcription

bio lecture 9.transcription - 9/11/2011 Transcription Dr....

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9/11/2011 1 Transcription Dr. Mark Holbrook Essential Functions of Genes Contain Information Can be Replicated Produce traits Transcription Genetic information observable traits Genetic code RNA Transcription (DNA info RNA info )
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9/11/2011 2 Molecular Mechanism? Genetic information Traits of organisms (DNA) ? 3 different genes X X X mutants fail to grow in absence of Arginine mutants grow 17.2 Neurospora crassa One Gene-One Enzyme Hypothesis Trait growth/no growth determined by presence/absence of enzyme(s) Defect of one gene = Defect of one enzyme Enzymes and genes have a one-to-one relationship. It is an oversimplification of the reality of the situation (you will discuss in detail in 2:11)
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9/11/2011 3 (Proteins) What is the molecular mechanism that can use the information in DNA to make specific proteins? Genetic information Traits of organisms (DNA) Molecular Mechanism? Flow of Genetic Information DNA RNA Polypeptide Translation Transcription One gene - one polypeptide (or RNA) Eukaryotic cell 17.3 RNA ( R ibo n ucleic a cid) Polyribonucleotide Ribose instead of deoxyribose sugar Phosphate Nitrogenous bases C, U , A, G. 1 5 7 1 5
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9/11/2011 4 Base Pairing between DNA and RNA Transcription From DNA RNA 3 -A A A T T T C C C G G G ----- (DNA) 5’ - U U U A AA GGG C C C ------ (RNA) Complementary pairing Same language Information is transcribed from DNA to RNA Flow of Genetic Information DNA RNA Transcription Polypeptide Translation Polyribonucleotide Poly deoxy ribonucleotide
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This note was uploaded on 10/11/2011 for the course BIO 010 taught by Professor Holbrook during the Spring '11 term at Iowa State.

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bio lecture 9.transcription - 9/11/2011 Transcription Dr....

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