exam 2 lecture 21

exam 2 lecture 21 - Biology 313 Lecture 21 Oct 13, 2010...

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Biology 313 Lecture 21 Oct 13, 2010
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Review: 2 Principles of Map-making 1. If RF is 50%: genes are very far apart on the same chromosome or on different chromosomes 2. Map distances, especially when genes are not tightly linked, are an underestimate due to double crossovers (DCO)
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But it looks like no CO have occurred if scoring A & B genes!!! 2 crossovers in this meiosis
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Two point and Three point testcrosses are used to construct genetic maps Two point testcross: between 2 genes Three point testcross: between 3 genes
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Chapter 7 : Linkage, Recombination and Gene Mapping 4 major topics Linkage Crossing over & recombination frequencies Gene mapping: two point testcross Gene mapping: three point testcross
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9 steps to map genes using a three point testcross (p. 181) Example is Drosophila: what is the genetic map in the region of chromosome 3 for the genes: scarlet eyes (st), recessive to red eyes (st+) ebony body color (e), recessive to gray (e+) small bristles (called spineless) (ss) recessive to normal bristles (ss+)
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exam 2 lecture 21 - Biology 313 Lecture 21 Oct 13, 2010...

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