Lecture 4 - Biology 313 Lecture 4 August 30, 2010 Chapter 3...

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Biology 313 Lecture 4 August 30, 2010
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Chapter 3 Basic Principles of Heredity 3.1 Gregor Mendel Discovered the Basic Principles of Heredity 3.2 Monohybrid Crosses Reveal the Principle of Segregation and the Concept of Dominance 3.3 Dihybrid Crosses Reveal the Principle of Independent Assortment 3.4 Observed Ratios of Progeny May Deviate from Expected Ratios by Chance
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Concept Checks: 1- 8 Worked Problems: 1 - 4 Comprehension Questions 1 – 11 Application Questions /Problems: 12 – 38 (Only do the starred* questions) (14 questions)
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3.1 Gregor Mendel Discovered the Basic Principles of Heredity Gregor Mendel (Austrian priest) discovered the basic principles of inheritance by breeding garden pea plants Published results in 1866 (rediscovered 1900) His choice of experimental subject had many advantages
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Practice Quiz List four reasons why pea was a good model experimental system for Mendel’s studies of heredity. Would cattle be a good system? Corn? Humans?
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Advantages of pea Easy to grow Has a short life span (fertilization to death) takes several months, so can observe a wide range of phenotypes at all life stages Produce many offspring Many varieties are “true breeding” (near isogenic, except for a single gene) Varieties differ from one another in easily distinguishable forms (phenotypes)
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e.g., A and a are alleles of gene “A”
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ruby eyes (rb) is at locus 76.0 100.0 1.0 50.0 200.0 300.0 400.0 cM cM = centiMorgan (a measure of physical distance on a chromosome) Genes are italicized
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AABbCcDdEe…… 25,000 genes in humans, plants, 4377 genes in E. coli Aa AA or aa It takes as many genes to make a plant as it does a human!
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biochemical or behavioral
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This note was uploaded on 10/06/2011 for the course BIO 313 taught by Professor Rodermel during the Spring '11 term at Iowa State.

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Lecture 4 - Biology 313 Lecture 4 August 30, 2010 Chapter 3...

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