lecture 6 exam 3 - Biology 313 Lecture 28 Nov 1 2010...

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Biology 313 Lecture 28 Nov 1, 2010
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Wednesday 3 November  Room 118 Horticulture @ 7 pm FREE PIZZA & POP! (for dues-paying members) Dr. Stephan Schneider, GDCB “Annelids, ancestors, and axis formation: Tracing developmental regulators in animal evolution”
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We are now finished with Transmission Genetics and moving into the exciting realm of Molecular Genetics
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Chapter 10 : DNA– Chemical Nature of the Gene Readings: all Problems All Concept Checks All Worked Problems Comprehension and Application Questions at end of Chapter: all starred
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Purpose of this chapter How DNA was identified as the genetic material (or is it protein?) 1950’s (Eisenhower, TV, Red scare, Polio, Korean War, explosion of babies and colleges post-WWII, rise of the research university; suburbia DNA structure: how is its structure related to its function?
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The key properties of genetic material 1. Must be able to store complex information for an organism’s phenotype 2. Must be able to translate the information into a phenotype 3. Must be able to replicate the information faithfully 4. Must allow for a mechanism of variation (e.g., by mutation)
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Chemistry of DNA/RNA Friedrich Miescher (time of Mendel-- 1860’s): chemistry of pus (pustules), have white blood cells, big nuclei; identified “ nuclein ” from the nuclei– an unkown compound that was acidic and rich in phosphorus: later named nucleic acid Hypothesis (1880’s): hereditary material resides in nucleus, probably in chromatin ” ( nucleic acid + proteins ): which one?
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