lecture 8 exam 2

lecture 8 exam 2 - Biology 313 Lecture 18 Oct 6, 2010 3...

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Biology 313 Lecture 18 Oct 6, 2010
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3 Techniques to Study Human Heredity 1. Pedigrees 2. Twin studies 3. Adoption studies
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Twin Studies Two types of twins: whether develop from one or two zygotes (a zygote is a fertilized egg, thus 2n) Monozygotic (MZ): develop from a single egg, fertilized by a single sperm, that splits into 2 embryos (100% genetically identical); identical twins Dizygotic (DZ): develop from 2 eggs fertilized by two separate sperm (~50% genes are shared in common, same % as all siblings)
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Concordance Comparisons of DZ and MZ twins can tell relative importance of genetic versus environmental factors in determining a trait Concordance : percentage of twin pairs that have the trait Discordance : when only one of the twins has the trait
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Contemporary examples of twin studies: Alcoholism, Obesity, Homosexuality We’ll consider Obesity: -epidemic: 33% of US adults -increased susceptibility to heart disease, diabetes, cancers -crudely measured by BMI
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Body Mass Index a measure of someone's weight in relation to height BMI= 703 X weight (pounds) / height (inches) 2 overweight is a BMI greater than 25; obese is a BMI greater than 30 SRR: 703 (182) / 72 2 = 24.6 (too many chips) Yang: 703 (150) / 69 2 = 22 (perfection)
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lecture 8 exam 2 - Biology 313 Lecture 18 Oct 6, 2010 3...

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