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Lecture 5-6-HWE - Hardy-Weinberg Equilibrium Mechanisms of...

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Hardy-Weinberg Equilibrium; Mechanisms of Speciation Evolutionary Analysis: Chap. 6-7; 16
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34 mice 3 phenotypes: Brown Grey Black 3 genotypes: aa Aa AA <—aa <—Aa, aA <—AA
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Will the allele frequencies of this population change over time?
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Population genetics If there is no selection ....
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Population genetics If there is no selection .... If there is no migration ....
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Population genetics If there is no selection .... If there is no migration .... If the population is large ....
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Population genetics If there is no selection .... If there is no migration .... If the population is large .... If mating is random ....
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Population genetics If there is no selection .... If there is no migration .... If the population is large .... If mating is random .... Then meiosis and recombination do not alter allele frequencies
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Population genetics Hardy-Weinberg equilibrium occurs when there is no change in allele frequencies
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Population genetics Hardy-Weinberg equilibrium occurs when there is no change in allele frequencies Equilibrium is reached in 1 generation and remains stable unless acted on by some other force
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Population genetics Do allele frequencies tend to change in a population over time?
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Population genetics Do allele frequencies tend to change in a population? Hardy-Weinberg says no
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Hardy-Weinberg Equilibrium Consider a population with two alleles, A and a. p = freq. of “A” allele q = freq. of “a” allele p + q = 1 Calculates allele frequencies in population
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Hardy-Weinberg Equilibrium p 2 (AA) + 2pq (Aa) + q 2 (aa) = 1 p = freq. of “A” allele q = freq. of “a” allele pq = “Aa” alleles (2pq because “Aa” or “aA”) Calculates genotypes in population
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Population genetics Hardy-Weinberg equilibrium explains why dominant alleles don’t replace recessive alleles in a population
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Population genetics Hardy-Weinberg equilibrium is RARE in nature!
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Population genetics If allele frequencies deviate from Hardy- Weinberg equilibrium .....
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Population genetics If allele frequencies deviate from Hardy- Weinberg equilibrium ..... ...then evolutionary processes are occurring!
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Population genetics This is because in nature there is Selection ....
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Population genetics This is because in nature there is Selection .... Migration (gene flow) ....
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