29 Specific immunity - Biology141 (Physiology) 4/6/08 1:16...

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4/6/08 1:16 AM Biology141 (Physiology) Page 1 of 3 https://courses.bio.psu.edu/spring2008/biol141/Lecture%2029(2008).htm Biology141 (Physiology) Lecture 29 M. Whim SPECIFIC (ADAPTIVE) IMMUNITY. [1]. CELLS INVOLVED IN ADAPTIVE IMMUNITY cont . (a). B lymphocytes. see lecture 28. (b). T lymphocytes. produced in the t hymus. don’t secrete antibodies: instead T cells must interact closely with the target cell. there are several different types of T cells: (i). Cytotoxic (killer) T lymphocytes these directly destroy cells that have foreign molecules on their surface. killer T cells are thus the “effector” cells of cellular immunity . killer T cells use cell-mediated destruction : i.e. actual contact with target cells. how are cytotoxic T cells activated? infected cells of the body display fragments (antigens) of the pathogen on their surface together with molecules called “MHC” molecules. the combination of an MHC molecule + antigen activates
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This note was uploaded on 04/05/2008 for the course BIOL 141 taught by Professor Viti,janehartwel during the Spring '08 term at Pennsylvania State University, University Park.

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29 Specific immunity - Biology141 (Physiology) 4/6/08 1:16...

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