Exam #3 Notes - Viruses and Prions (March 17, 2009) I....

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Viruses and Prions (March 17, 2009) I. Viruses a. Germ – organism that causes a disease b. Most common virus disease – common cold c. Pandemic – when an epidemic breaks out into several countries d. Last pandemic was Hoof and Mouth Disease i. Right after “Mad Cow” disease ii. Affects ungulates iii. Disinfecting and Burning countered the virus iv. Vaccines not use, b/c although the animal was free of symptoms, it still carried and passed the virus e. Virses are smaller than bacteria, and are not an organism Virus Prokaryote Eukaryote Consists of a cell? NO YES YES Metablolize? NO YES YES Respond to stimuli? NO YES YES Multiply? YES YES YES Evolve? YES YES YES Sensitive to Antibiotics? NO YES NO f. What does anti-biotic mean i. Resistance to g. What is a virus? i. “non-cellular, non-living infectious particle” h. Characteristics of a virus i. Has the following part 1. Nucleic Acid ( either DNA or RNA) a. Single or doubled stranded, but never both 2. Usually Coated with a Protein 3. May be surrounded by an Envelope a. Steals it from the host cell i. Where do viruses get their name? i. (In book) j. How do viruses multiply? i. Virus attaches to host cell 1. Inserts DNA or RNA into cell ii. Virus uses host cell’s machinery to reproduce DNA/RNA and proteins iii. Virus assembles protein coat, DNA/RNA iv. Virus makes enzymes that rupture the cell membrane, and the cell lyses” (splits open) 1. This is the LYTIC pathway of multiplication v. LYSONGENIC pathway is the same, except for step 2, where the viral DNA is actually incorporated into the DNA of the cell k. Some important viral disease
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i. Colds ii. Influenza (flu) iii. Herpes (I and II) iv. AIDS v. Ebola vi. Hepatitis B vii. Warts (some) viii. Mononucleosis ix. Yellow Fever x. Rabies xi. Measles xii. Smallpox xiii. Mumps l. How can RNA join our DNA? i.
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Exam #3 Notes - Viruses and Prions (March 17, 2009) I....

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